The liturgy of the Church of South India combines many traditions, including that of the Methodists and such smaller churches as the Church of the Brethren and the Disciples of Christ. After the formation of the Church of South India the first synod met at Madurai in March 1948 and appointed a liturgical committee. The first Synod in 1948 (where the Holy Communion service was that of the Presbyterian Church of Scotland) appointed a liturgy committee, composed mainly of Western theologians. The liturgy so prepared was first used at the Synod Session in 1950 and approved for use throughout the church "wherever it is desired" in 1954. The first version of the Confirmation Service for the new church was also released in 1950, translated into regional languages and was quickly adopted by the various dioceses.

By 1962 the Liturgy Committee was able to prepare a number of Orders. They were Eucharist, Morning and Evening Prayer, Marriage Service, Burial Service, Ordination Service and Covenant Service (1954), Holy Baptism (1955) and Almanac (1955–56). The Book of Common Worship of the CSI was published in 1963 with all the above orders of service. The orders of service consist of: Order for Morning and Evening Worship, Order of Service for the Baptized Persons, Order for Holy Baptism, Order for the Churching of Women, Order for Holy Matrimony, Order for the Burial Service, Order for the Covenant Service, Order for Ordination Services.

The CSI liturgy was again revised in the year 2004 and published as a hardback book in 2006. The CSI Synod Liturgical Committee has developed several new orders for worship for different occasions. The order for the Communion Service, known as the CSI Liturgy, has been internationally acclaimed as an important model for new liturgies. The Committee has also produced three different cycles of lectionaries for daily Bible readings and "propers", and collects for Communion services. In addition, the Committee has also brought out a Supplement to the Book of Common Worship.